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KMID : 0361120080220010135
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Korean Journal of Transplantation
2008 Volume.22 No. 1 p.135 ~ p.137
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A Case of Invasive Aspergillosis in Transplanted Kidney and Perirenal Area
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Na Hyun-Hee
Hong Seong-Woo
Kim Mun-Cheol
Kang Yun-Kyung
Yoon Young-Chul
Koh Haeng-Il
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Abstract
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Recently, the incidence of fungal infection increases because of immunosuppressive therapy and chemotherapy. In immunosuppressed transplant recipients, Aspergillus can be a dangerous pathogen, capable of inducing fulminant clinical disease. Invasive fungal infections are life-threatening complications in solid-organ transplantation. Although the rate of fungal infections in transplant recipients is lower than that of other infections, the mortality rate is higher. A 34 year-old male was admitted to our hospital with fever and gross hematuria. He had received renal transplantation 2 years ago and had been transferred the other hospital 1 month ago. Initial laboratory data evaluation showed a pancytopenia and azotemia. We thought that pancytopenia was caused by immunosuppressive agents and infection. The patient was treated with antibiotics but fever was not subsided. After 4 days, he complained of transplant site pain and tenderness to percussion. A percutaneous renal biopsy was performed. Microscopic examination showed invasive aspergillosis in transplanted kidney and perirenal area. We removed the transplanted kidney and perirenal tissue, and prescribed antifungal agents for 3 months.
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KEYWORD
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Aspergillus, Invasive aspersillosis, Kidney transplantation
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